N-(2-苯甲酰基-4-氯-苯基)乙酰胺合成路线 (共 18 条)
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=25°C; 16 h;
参考文献
Patterson, Stephen; Alphey, Magnus S.; Jones, Deuan C.; Shanks, Emma J.; Street, Ian P.; Frearson, Julie A.; Wyatt, Paul G.; Gilbert, Ian H.; Fairlamb, Alan H.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6514 - 6530
反应条件
tert.-butylhydroperoxide; palladium diacetate in dimethyl sulfoxide T=100°C; 20 h; regioselective reaction;
参考文献
Yin, Zhangwei; Sun, Peipei
Journal of Organic Chemistry, 2012 , vol. 77, # 24 p. 11339 - 11344
反应条件
in ethanol T=0 - 20°C; Inert atmosphere;
参考文献
Martjuga, Marina; Shabashov, Dmitry; Belyakov, Sergey; Liepinsh, Edvards; Suna, Edgars
Journal of Organic Chemistry, 2010 , vol. 75, # 7 p. 2357 - 2368
反应条件
tert.-butylhydroperoxide; trifluorormethanesulfonic acid; palladium diacetate; acetic acid in N,N-dimethyl acetamide T=90°C; 5 h;
参考文献
Yuan, Yu; Chen, Duanteng; Wang, Xiaowei
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 18 p. 3373 - 3379
反应条件
1: dichloromethane / 20 °C 2: tert.-butylhydroperoxide; trifluorormethanesulfonic acid; palladium diacetate; acetic acid / N,N-dimethyl acetamide / 5 h / 90 °C View Scheme
参考文献
Yuan, Yu; Chen, Duanteng; Wang, Xiaowei
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 18 p. 3373 - 3379
反应条件
sodium acetate 70 h; Heatingother aryl- and alkylketones, and anilines under various conditions; Product distributionMechanism;
参考文献
Peet, Norton P.; Sunder, Shyam; Barbuch, Robert J.; Whalon, Michael R.; Huber, Edward W.; Huffman, John C.
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1611 - 1618
反应条件
hydrogenchloride; acetic acid im geschlossenen Rohr;
参考文献
Chattaway
Journal of the Chemical Society, 1904 , vol. 85, p. 342
参考文献
Hino; Furukawa; Nagai; Uno
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 9 p. 2618 - 2622
反应条件
T=100°C; im geschlossenen Rohr;
参考文献
Chattaway
Journal of the Chemical Society, 1904 , vol. 85, p. 342
参考文献
Chattaway
Journal of the Chemical Society, 1904 , vol. 85, p. 342