2-甲基-[1,8]-萘啶合成路线 (共 23 条)
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2679 - 2684
反应条件
iron sulphate heptahydrate; sulfuric acid; boric acid in water; glycerol T=0 - 135°C; 4 h;
参考文献
Liu, Xingjiang; Chen, Mingxing; Liu, Ziping; Yu, Mingming; Wei, Liuhe; Li, Zhanxian
Tetrahedron, 2014 , vol. 70, # 3 p. 658 - 663
反应条件
1: N-(2-pyridinyl)-2,2-dimethylpropanamide With n-butyllithium in tetrahydrofuran; hexane T=0°C; 3 h; 2: 1-methyl-3-dimethylaminoprop-2-enone in tetrahydrofuran; hexane T=-70 - 0°C; 3 h; 3: With hydrogenchloride 4 h; Heating;
参考文献
Synlett, , # 3 p. 379 - 382
反应条件
potassium hydroxide in ethanol Friedlaender reaction; 8 h; Heating;
参考文献
Heterocycles, , vol. 65, # 11 p. 2777 - 2782
反应条件
1: 67 percent / DIEA / CH2Cl2 2: 95 percent / LDA 3: 52 percent / aq. HCl 4: 99 percent / L-proline View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2679 - 2684
反应条件
1: 95 percent / LDA 2: 52 percent / aq. HCl 3: 99 percent / L-proline View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2679 - 2684
反应条件
1: 52 percent / aq. HCl 2: 99 percent / L-proline View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2679 - 2684
反应条件
sulfolane; triphenylphosphine T=151°C; Rate constant;
参考文献
Australian Journal of Chemistry, , vol. 34, # 1 p. 163 - 170
反应条件
1: 74 percent / H2 / Pd/C / ethanol 2: 50 percent / NaH / tetrahydrofuran 3: LDA / tetrahydrofuran / 0 °C 4: NaOH / methanol View Scheme
参考文献
Leonard, Kristi; Pan, Wenxi; Anaclerio, Beth; Gushue, Joan M.; Guo, Zihong; DesJarlais, Renee L.; Chaikin, Marge A.; Lattanze, Jennifer; Crysler, Carl; Manthey, Carl L.; Tomczuk, Bruce E.; Marugan, Juan Jose
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2679 - 2684