oxygen; Cu-X zeolite in 1,2-dichloro-ethane; acetonitrile T=50°C; Oxidation; Oxidative cleavage; 5 h;

oxygen; Cu-X zeolite in 1,2-dichloro-ethane; acetonitrile T=50°C; Oxidation; Oxidative cleavage; 5 h;

potassium dichromate; sulfuric acid in diethyl ether T=25°C; 1 h;

in tetrahydrofuran under N2, dropwise addn. of BF3*Et2O to a suspension of NaBH4 in THF at 25°C with stirring, addn. of morpholino derivate after 1h, stirred for additional 3h at 25°C; slowly quenched with MeOH, addn. of NaOH, solvent evapn. (25°C, 12 Torr), alkaline aq. layer cooled to 0°C and acidified (concd. HCl), boronic acid extd.(ether), washed (H2O), dried (MgSO4), evapn.;

sodium hydroxide; sodium tetrahydroborate; boron trifluoride diethyl etherate; dihydrogen peroxide 1.) THF, 25 deg C, 3 h, 2.) ether, 25 deg C, 3 h; Yield given. Multistep reaction;

in chloroform T=40°C; 24 h; Further byproducts given;

in dichloromethane T=45°C; 4 h;