3-(4-甲氧基苯氧基)-1,2-丙二醇合成路线 （共 8 条）
反应条件
1: 100 percent / SOCl2, pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 98 percent / NaIO4, RuCl3*H2O / acetonitrile; H2O / 0.33 h / Ambient temperature 3: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 10 min. 2.) THF, room temperature View Scheme
参考文献
He, Linli; Byun, Hoe-Sup; Bittman, Robert
Journal of Organic Chemistry, 1998 , vol. 63, # 16 p. 5696 - 5699
反应条件
di(n-butyl)tin oxide; cesium fluoride 1.) CHCl3, MeOH, reflux, 3 h, 2.) DMF, r.t., 24 h; 90 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Byun, Hoe-Sup; Kumar, Erukulla Ravi; Bittman, Robert
Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2630 - 2633
反应条件
di(n-butyl)tin oxide; cesium fluoride 1.) MeOH, reflux, 2.) DMF, RT; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Marino-Albernas, Jose R.; Bittman, Robert; Peters, Andrew; Mayhew, Eric
Journal of Medicinal Chemistry, 1996 , vol. 39, # 17 p. 3241 - 3247
反应条件
sodium periodate; silica gel in dichloromethane; water
T=25°C; 2 h;
参考文献
Guimond, Nicolas; MacDonald, Melissa J.; Lemieux, Valerie; Beauchemin, Andre M.
Journal of the American Chemical Society, 2012 , vol. 134, # 40 p. 16571 - 16577,7
Title/Abstract Full Text Show Details
Guimond, Nicolas; MacDonald, Melissa J.; Lemieux, Valerie; Beauchemin, Andre M.
Journal of the American Chemical Society, 2012 , vol. 134, # 40 p. 16571 - 16577
反应条件
sodium periodate in water; ethyl acetate
参考文献
Boehringer Mannhein Italia, S.p.A.
Patent: US4968706 A1, 1990 ;
反应条件
sodium periodate; sodium ethanolate in ethanol; water
参考文献
Boehringer Biochemia Robin S.p.A.
Patent: US4988701 A1, 1991 ;
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in benzene
24 h; Heating;
参考文献
Byun, Hoe-Sup; Sadlofsky, Jason A.; Bittman, Robert
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2560 - 2563
反应条件
sodium periodate in water; ethyl acetate
参考文献
Boehringer Mannhein Italia, S.p.A.
Patent: US4968706 A1, 1990 ;
