4-苯基-3-丁炔-2-酮合成路线 （共 131 条）
参考文献
v. Auwers; Stuhlmann
Chemische Berichte, 1926 , vol. 59, p. 1054
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I) in toluene
T=110°C; 5 h;
参考文献
Wender, Paul A.; Paxton, Thomas J.; Williams, Travis J.
Journal of the American Chemical Society, 2006 , vol. 128, # 46 p. 14814 - 14815
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; diethyl ether
T=20°C; 12 h;
参考文献
Hanzawa, Yuji; Tabuchi, Nobuhito; Narita, Kensuke; Kakuuchi, Akito; Yabe, Masaya; Taguchi, Takeo
Tetrahedron, 2002 , vol. 58, # 38 p. 7559 - 7571
反应条件
1: Lindlar reduction
2: tetrahydrofuran / 0.5 h / 0 °C
View Scheme
参考文献
Corey, E. J.; Boaz, Neil W.
Tetrahedron Letters, 1985 , vol. 26, # 49 p. 6015 - 6018
反应条件
1: triphenyl-methyl-phosphonium iodide With potassium tert-butylate in benzene
Wittig Olefination; 1 h; Cooling with iceRefluxInert atmosphere;
2: 4-phenyl-3-butyn-2-one in benzene
T=20°C; Wittig Olefination; Cooling with iceInert atmosphere;
参考文献
Maity, Soham; Manna, Srimanta; Rana, Sujoy; Naveen, Togati; Mallick, Arijit; Maiti, Debabrata
Journal of the American Chemical Society, 2013 , vol. 135, # 9 p. 3355 - 3358
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium
2: 4-phenyl-3-butyn-2-one Wittig Olefination;
参考文献
Haubenreisser, Stefan; Hensenne, Peter; Schroeder, Sebastian; Niggemann, Meike
Organic Letters, 2013 , vol. 15, # 9 p. 2262 - 2265
反应条件
sodium hydroxide; ethylenediaminetetraacetic acid; dihydrogen peroxide in water
T=25°C; 10 h; mechanism; energy data: ΔH(excit.), ΔS(excit.); other electron deficient acetylenes and related compounds, other alcohol, var. temp. and reagent ratio; KineticsRate constantProduct distribution;
参考文献
Sawaki; Inoue; Ogata
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 4 p. 1133 - 1138
反应条件
1: ammonium hydroxide / ethanol / 7 h / Heating
2: 81 percent
3: 76 percent / dimethylformamide / 6 h / Heating
View Scheme
参考文献
Liso, Gaetano; Trapani, Giuseppe; Reho, Antonia; Latrofa, Andrea; Loiodice, Fulvio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 567 - 572
反应条件
ammonia; iodine in water
T=60°C; Lieben-Haller-Bauer reaction; 3 h;
参考文献
Cao, Liping; Ding, Jiaoyang; Gao, Meng; Wang, Zihua; Li, Juan; Wu, Anxin
Organic Letters, 2009 , vol. 11, # 17 p. 3810 - 3813
反应条件
in ethanol
7 h; Heating;
参考文献
Liso; Trapani; Berardi; Marchini
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 2 p. 377 - 379
