(S)-(-)-N-乙酰基-1-甲基苄胺合成路线 （共 50 条）
反应条件
1: H2NOSO3H / tetrahydrofuran / 10 h
2: 1,1'-carbonyldiimidazole / toluene
View Scheme
参考文献
Fernandez, Elena; Maeda, Kenji; Hooper, Mark W.; Brown, John M.
Chemistry - A European Journal, 2000 , vol. 6, # 10 p. 1840 - 1846
反应条件
Candida antarctica lipase B; C70H58O14Ru2; sodium carbonate in toluene
T=90°C; 72 h; optical yield given as percent ee;
参考文献
Thalen, Lisa K.; Baeckvall
Beilstein Journal of Organic Chemistry, 2010 , vol. 6, p. 823 - 829
反应条件
sodium tetrahydroborate; nickel dichloride in methanol
参考文献
Toshimitsu, Akio; Hirosawa, Chitaru; Tanimoto, Shigeo
Tetrahedron Letters, 1991 , vol. 32, # 34 p. 4317 - 4320
反应条件
1: 81 percent / benzophenone / benzene / Irradiation
2: 1) t-BuOK, 2) pyridine / 1) ether, H2O, RT, 2) benzene, reflux
View Scheme
参考文献
Kohmoto, Shigeo; Kreher, Thomas; Miyaji, Yoshiyuki; Yamamoto, Makoto; Yamada, Kazutoshi
Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3490 - 3492
反应条件
triethylamine in tetrahydrofuran
T=20°C; 10 h;
参考文献
Hirose, Takuji; Begum, Muksana; Sadequl Islam; Taniguchi, Kayoko; Yasutake, Mikio
Tetrahedron Asymmetry, 2008 , vol. 19, # 14 p. 1641 - 1646
反应条件
Candida antarctica lipase B immobilized on acrylic resin in toluene
T=25°C; 0.0666667 h; Resolution of racemateFlow reactor; TemperatureTime;
参考文献
De Miranda, Amanda S.; Miranda, Leandro S. M.; De Souza, Rodrigo O. M. A.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 20 p. 3332 - 3336
反应条件
1,1'-carbonyldiimidazole in toluene
Acetylation; Title compound not separated from byproducts;
参考文献
Fernandez, Elena; Maeda, Kenji; Hooper, Mark W.; Brown, John M.
Chemistry - A European Journal, 2000 , vol. 6, # 10 p. 1840 - 1846
反应条件
2,2'-azo-bisisobutyronitrile; triphenylstannane in benzene
reductive deselenenylation; 3 h; Heating;
参考文献
Tiecco, Marcello; Testaferri, Lorenzo; Santi, Claudio; Tomassini, Cristina; Marini, Francesca; Bagnoli, Luana; Temperini, Andrea
European Journal of Organic Chemistry, 2000 , # 20 p. 3451 - 3457
反应条件
Aliquatreg; 336 in tetrahydrofuran
T=20°C; Product distribution; Further Variations:ReagentsSolventsTemperatures;
参考文献
Arseniyadis, Stellios; Subhash, Pithani V.; Valleix, Alain; Mathew, Suju P.; Blackmond, Donna G.; Wagner, Alain; Mioskowski, Charles
Journal of the American Chemical Society, 2005 , vol. 127, # 17 p. 6138 - 6139
反应条件
triethylamine in diethyl ether; N-dodecane; dichloromethane; toluene
参考文献
Jerphagnon, Thomas; Gayet, Arnaud J.A.; Berthiol, Florian; Ritleng, Vincent; Mrsic, Natasa; Meetsma, Auke; Pfeffer, Michel; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G.
Chemistry - A European Journal, 2009 , vol. 15, # 46 p. 12780 - 12790
