米氏酸合成路线 - 魔法化学

参考文献

Sifferlen, Thierry; Boss, Christoph; Cottreel, Emmanuelle; Koberstein, Ralf; Gude, Markus; Aissaoui, Hamed; Weller, Thomas; Gatfield, John; Brisbare-Roch, Catherine; Jenck, Francois
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1539 - 1542

462-08-83-氨基吡啶+

2033-24-1米氏酸

851680-50-7

参考文献

Methylgene, Inc.
Patent: US2007/4675 A1, 2007 ;
Location in patent: Page/Page column 74 ;
US 20070004675 A1

2033-24-1米氏酸+

75-36-5乙酰氯

85920-63-45-(1-羟基乙亚基)-2,2-二甲基-1,3-二氧杂环己-4,6-二酮

参考文献

Sorensen, Ulrik S.; Falch, Erik; Krogsgaard-Larsen, Povl
Journal of Organic Chemistry, 2000 , vol. 65, # 4 p. 1003 - 1007

2033-24-1米氏酸+

78-39-7原乙酸三乙酯

85920-63-45-(1-羟基乙亚基)-2,2-二甲基-1,3-二氧杂环己-4,6-二酮

参考文献

Akue-Gedu, Rufine; El-Hafidi, Hayate; Rigo, Benoit; Couturier, Daniel
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 2 p. 365 - 369

2033-24-1米氏酸+

64-19-7醋酸

85920-63-45-(1-羟基乙亚基)-2,2-二甲基-1,3-二氧杂环己-4,6-二酮

参考文献

Guthrie, Daryl A.; Kim, Nam Y.; Siegler, Maxime A.; Moore, Cathy D.; Toscano, John P.
Journal of the American Chemical Society, 2012 , vol. 134, # 4 p. 1962 - 1965

2033-24-1米氏酸

85920-63-45-(1-羟基乙亚基)-2,2-二甲基-1,3-二氧杂环己-4,6-二酮

参考文献

Habibi, Azizollah; Eskandari, Khalil; Alizadeh, Abdolali
Phosphorus, Sulfur and Silicon and the Related Elements, 2012 , vol. 187, # 9 p. 1109 - 1117

1455-77-23,5-二氨基-1,2,4-三氮唑+

参考文献

Lipson; Borodina; Shirobokova; Desenko; Shishkin; Zubatyuk
Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 4 p. 490 - 495

1455-77-23,5-二氨基-1,2,4-三氮唑+

参考文献

Lipson; Borodina; Shirobokova; Desenko; Shishkin; Zubatyuk
Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 4 p. 490 - 495

2033-24-1米氏酸+

108-12-3异戊酰氯

86238-65-5

参考文献

Reverchon, Sylvie; Chantegrel, Bernard; Deshayes, Christian; Doutheau, Alain; Cotte-Pattat, Nicole
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 8 p. 1153 - 1157

2033-24-1米氏酸+

3303-84-2

865364-92-7

参考文献

SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD.
Patent: WO2007/85188 A1, 2007 ;
Location in patent: Page/Page column 107; 112 ;
WO 2007/085188 A1