1,4-二硫螺[4.5]-8-癸醇合成路线 （共 10 条）
反应条件
iodine in chloroform T=23°C; 18 h; Inert atmosphere;
参考文献
Overman, Larry E.; Tanis, Paul S.
Journal of Organic Chemistry, 2010 , vol. 75, # 2 p. 455 - 463
反应条件
lithium aluminium tetrahydride in diethyl ether T=0°C; 1 h;
参考文献
Takemura, Tetsuo; Hosoya, Yoshiko; Mori, Nobuo
Canadian Journal of Chemistry, 1990 , vol. 68, # 4 p. 523 - 529
反应条件
potassium hydroxide in methanol 3 h; Heating;
参考文献
Meyer, Walter L.; Brannon, Michael J.; Burgos, Celmira da G.; Goodwin, Thomas E.; Howard, Ralph W.
Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 438 - 447
反应条件
sodium methylate in methanol 15 h; Heating;
参考文献
Crombie, Leslie; Crombie, W. Mary L.; Jamieson, Sally V.; Tuchinda Patoomratana; Whitaker, Alison J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1485 - 1492
反应条件
1: 87 percent / Et2O*BF3 / 0.17 h / 0 °C 2: 100 percent / aq. KOH / methanol / 3 h / Heating View Scheme
参考文献
Crombie, Leslie; Crombie, W. Mary L.; Jamieson, Sally V.; Tuchinda Patoomratana; Whitaker, Alison J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1485 - 1492
反应条件
1: Birch reduction 2: HCl / CHCl3 / 4 h / Ambient temperature View Scheme
参考文献
Bell, Vivien L.; Holmes, Andrew B.
Synthetic Communications, 1982 , vol. 12, # 4 p. 323 - 326
反应条件
hydrogenchloride in chloroform 4 h; Ambient temperature; Yield given;
参考文献
Bell, Vivien L.; Holmes, Andrew B.
Synthetic Communications, 1982 , vol. 12, # 4 p. 323 - 326
反应条件
1: 82 percent / chromium trioxide / acetic acid; H2O 2: 92 percent / toluene-p-sulphonic acid / benzene / Heating 3: 83 percent / sodium methoxide / methanol / 15 h / Heating View Scheme
参考文献
Crombie, Leslie; Crombie, W. Mary L.; Jamieson, Sally V.; Tuchinda Patoomratana; Whitaker, Alison J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1485 - 1492
反应条件
1: 25.5 percent / p-TsOH*H2O / benzene / Heating 2: 91.9 percent / LiAlH4 / diethyl ether / 1 h / 0 °C View Scheme
参考文献
Takemura, Tetsuo; Hosoya, Yoshiko; Mori, Nobuo
Canadian Journal of Chemistry, 1990 , vol. 68, # 4 p. 523 - 529
反应条件
phosphoric acid; dicyclohexyl-carbodiimide in dimethyl sulfoxide; benzene
3 h;
参考文献
Meyer, Walter L.; Brannon, Michael J.; Burgos, Celmira da G.; Goodwin, Thomas E.; Howard, Ralph W.
Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 438 - 447
