1-溴-4-(叔丁氧基甲基)苯合成路线 （共 5 条）
反应条件
sulfuric acid in dichloromethane
参考文献
Nassal, Michael
Liebigs Annalen der Chemie, 1983 , # 9 p. 1510 - 1523
反应条件
potassium sonication;
参考文献
Davis, Anthony P.; Orchard, Michael G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 8 p. 919 - 924
反应条件
1: 1) n-BuLi / 1) hexane, ether, -30 to 0 deg C in 2 h, 2) ether, -50 deg C, 3 h 2: 57 percent / NH3OHCl, NaOH / ethanol / 16 h / Heating 3: 87 percent / pyridine / 3 h / Heating 4: 80 percent / NH3 / diethyl ether / 12 h / Ambient temperature 5: 92 percent / Ag2O / diethyl ether / 1 h 6: 86 percent / TFA / CH2Cl2 / 2 h / Ambient temperature 7: 72 percent / 0.2N KOH, KMnO4 / dioxane / 2 h / Ambient temperature 8: 73 percent / N,N'-dicyclohexylcarbodiimide / dioxane; ethyl acetate / 6 h / Ambient temperature View Scheme
参考文献
Liebigs Annalen der Chemie, , # 9 p. 1510 - 1523
反应条件
1: 1) n-BuLi / 1) hexane, ether, -30 to 0 deg C in 2 h, 2) ether, -50 deg C, 3 h 2: 57 percent / NH3OHCl, NaOH / ethanol / 16 h / Heating 3: 87 percent / pyridine / 3 h / Heating 4: 80 percent / NH3 / diethyl ether / 12 h / Ambient temperature 5: 92 percent / Ag2O / diethyl ether / 1 h 6: 86 percent / TFA / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Liebigs Annalen der Chemie, , # 9 p. 1510 - 1523
反应条件
1: 1) n-BuLi / 1) hexane, ether, -30 to 0 deg C in 2 h, 2) ether, -50 deg C, 3 h 2: 57 percent / NH3OHCl, NaOH / ethanol / 16 h / Heating 3: 87 percent / pyridine / 3 h / Heating 4: 80 percent / NH3 / diethyl ether / 12 h / Ambient temperature 5: 92 percent / Ag2O / diethyl ether / 1 h 6: 86 percent / TFA / CH2Cl2 / 2 h / Ambient temperature 7: 72 percent / 0.2N KOH, KMnO4 / dioxane / 2 h / Ambient temperature View Scheme
参考文献
Nassal, Michael
Liebigs Annalen der Chemie, 1983 , # 9 p. 1510 - 1523
