1-甲基-4-苯基乙炔苯合成路线 （共 165 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide T=50 - 80°C;
参考文献
Lee, Hee Joon; Park, Kyungho; Bae, Goun; Choe, Jaehoon; Song, Kwang Ho; Lee, Sunwoo
Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5064 - 5067
反应条件
NiCl2((PPh3)P)2 in ethylene glycol dimethyl ether T=80°C; 4 h; Inert atmosphere;
参考文献
Biradar, Deepak B.; Gau, Han-Mou
Chemical Communications, 2011 , vol. 47, # 37 p. 10467 - 10469
反应条件
1: bromobenzene; acetylenecarboxylic acid With SPHOS; bis(η3-allyl-μ-chloropalladium(II)); tetra-n-butylammonium fluoride trihydrate in 1-methyl-pyrrolidin-2-one; water T=50°C; 16 h; Inert atmosphere; 2: para-bromotoluene in 1-methyl-pyrrolidin-2-one; water T=80°C; 14 h; Inert atmosphere;
参考文献
Tartaggia, Stefano; De Lucchi, Ottorino; Goossen, Lukas J.
European Journal of Organic Chemistry, 2012 , # 7 p. 1431 - 1438
反应条件
copper(l) iodide; 8-hydroxy-quinoline; potassium carbonate in N,N-dimethyl-formamide T=110°C; 24 h; Inert atmosphere;
参考文献
Yan, Hong; Lu, Linhua; Sun, Peng; Zhu, Yan; Yang, Hailong; Liu, Defu; Rong, Guangwei; Mao, Jincheng
RSC Advances, 2013 , vol. 3, # 2 p. 377 - 381
反应条件
[Pd((.eta.5-C5H5)Fe[(.eta.5-C5H3)C(Me)=N(C6H4-4-Me)])(.mu.-Cl)]2; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in anhydrous xylene; water T=120°C; 3 h;
参考文献
Li, Xi'Ang; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 9 p. 4543 - 4550
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
反应条件
t-Bu2P(biphenyl); tetrabutyl ammonium fluoride; tris-(dibenzylideneacetone)dipalladium(0) in tetrahydrofuran 12 h; Heating;
参考文献
Faller, Jack W.; Kultyshev, Roman G.; Parr, Jonathan
Tetrahedron Letters, 2003 , vol. 44, # 3 p. 451 - 453
反应条件
tri-tert-butyl phosphine; argon; hydrogen; potassium carbonate; tris-(dibenzylideneacetone)dipalladium(0); copper(l) iodide in tetrahydrofuran; hexane Sonogashira-Hagihara cross-coupling; Heating;
参考文献
Dubbaka, Srinivas Reddy; Vogel, Pierre
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1793 - 1797
反应条件
pyrrolidine; triphenylphosphine; 1-n-butyl-3-methylimidazolium tetrafluoroborate; bis(η3-allyl-μ-chloropalladium(II)) T=130°C; Heck alkynylation; 20 h;
参考文献
Hierso, Jean-Cyrille; Picquet, Michel; Cattey, Helene; Meunier, Philippe
Synlett, 2006 , # 18 p. 3005 - 3008
反应条件
tert.-butylnitrite; trifuran-2-yl-phosphane; palladium diacetate; acetic acid in dimethyl sulfoxide T=20 - 32°C; Sonogashira coupling; 16 h; Inert atmosphere;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Chemical Communications, 2011 , vol. 47, # 28 p. 7959 - 7961
