反应条件
1: 1-chloromethylcyclohexene With O,O'-(S)-(1,1'-dinaphthyl-2,2'-diyl)-N,N-di-(S,S)-[2-phenylethylphosphoramidite]; copper(I) thiophene-2-carboxylate in dichloromethane T=20°C; Inert atmosphere; 2: n-hexyl-magnesium bromide in diethyl ether; dichloromethane T=-78°C; 5 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Falciola, Caroline A.; Tissot-Croset, Karine; Reyneri, Hugo; Alexakis, Alexandre
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 7-8 p. 1090 - 1100