2',4'-二羟基-2-苯基苯乙酮合成路线 （共 57 条）
反应条件
tributyl-amine T=0°C; 1 h;
参考文献
Pivovarenko, V. G.; Khilya, V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 5 p. 497 - 502
Khimiya Geterotsiklicheskikh Soedinenii, Sbornik, 1992 , # 5 p. 595 - 600
参考文献
Narasimhachari et al.
Journal of Scientific and Industrial Research, 1953 , vol. 12 B, p. 287,291
Full Text Show Details
Iyer et al.
Proceedings - Indian Academy of Sciences, Section A, 1951 , # 33 p. 116,122
反应条件
unter einleiten von HCl und Erwaermen des Reaktionsprodukts mit H2O;
参考文献
Farkas
Chemische Berichte, 1957 , vol. 90, p. 2940,2943
参考文献
Sathe; Venkataraman
Current Science, 1949 , vol. 18, p. 373
反应条件
1: 95 percent / 1,4-diazabicyclo<2.2.2>octane / dimethylformamide / 2 h / Ambient temperature
2: 87 percent / various solvent(s) / 1 h / Heating
3: 67 percent / Raney nickel / ethanol / 1 h / Ambient temperature
View Scheme
参考文献
Levai; Sebok
Synthetic Communications, 1992 , vol. 22, # 12 p. 1735 - 1750
反应条件
1: 81.6 percent / morpholine / propan-2-ol / 7 h / 80 °C
2: 97.1 percent / K2CO3 / dimethylsulfoxide / 2 h / 20 °C
View Scheme
参考文献
Mahal; Rai; Venkataraman
Journal of the Chemical Society, 1934 , p. 1120
反应条件
potassium hydroxide; dimethyl sulfoxide
0.5 h;
参考文献
Saxena, Shabnam; Jain, P. K.; Makrandi, J. K.; Grover, S. K.
Tetrahedron Letters, 1983 , vol. 24, # 32 p. 3401 - 3402
反应条件
trifluoroacetic acid sodium salt
T=140°C; 14 h;
参考文献
Wu; Loch III; Toder; Borrelli; Gawlak; Radov; Gensmantel
Journal of Medicinal Chemistry, 1992 , vol. 35, # 19 p. 3519 - 3525
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=65 - 70°C; 5 h;
参考文献
Varga, Marton; Batori, Sandor; Koevari-Radkai, Maria; Prohaszka-Nemet, Ildiko; Vitanyi-Morvai, Magdolna; Boecskey, Zsolt; Bokotey, Sandor; Simon, Kalman; Hermecz, Istvan
European Journal of Organic Chemistry, 2001 , # 20 p. 3911 - 3920
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=0°C; Mitsunobu reaction; 0.166667 h;
参考文献
Su, Bin; Hackett, John C.; Diaz-Cruz, Edgar S.; Kim, Young-Woo; Brueggemeier, Robert W.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 23 p. 6571 - 6577
