1-哌啶-1-基环己烷甲腈合成路线 （共 34 条）
反应条件
magnesium sulfate in N,N-dimethyl acetamide T=45°C; 48 h;
参考文献
Ilagouma, A. T.; Dornand, J.; Liu, C. F.; Zenone, F.; Mani, J. C.; Kamenka, J. M.
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 7 p. 609 - 615
反应条件
Co(II) complex supported on mesoporous SBA-15 T=40°C; Strecker-type reaction; 3 h;
参考文献
Rajabi, Fatemeh; Nourian, Saghar; Ghiassian, Sara; Balu, Alina M.; Saidi, Mohammad Reza; Serrano-Ruiz, Juan Carlos; Luque, Rafael
Green Chemistry, 2011 , vol. 13, # 11 p. 3282 - 3289
参考文献
Ahmadi, Abbas; Solati, Jalal; Hajikhani, Ramin; Pakzad, Sara
Asian Journal of Chemistry, 2011 , vol. 23, # 12 p. 5429 - 5432
反应条件
in neat (no solvent) T=60 - 70°C;
参考文献
Popov; Mokhov; Tankabekyan
Russian Journal of Organic Chemistry, 2014 , vol. 50, # 1 p. 21 - 24
Zh. Org. Khim., 2014 , vol. 50, # 1 p. 29 - 32,4
反应条件
sodium hydrogensulfite T=20°C;
参考文献
Ogunbadeniyi, Alaba M.; Adejare, Adeboye
Journal of Fluorine Chemistry, 2002 , vol. 114, # 1 p. 39 - 42
反应条件
zinc(II) iodide in methanol; diethyl ether T=80°C; Strecker reaction; 8 h;
参考文献
McClure, Kelly J.; Maher, Michael; Wu, Nancy; Chaplan, Sandra R.; Eckert III, William A.; Lee, Dong H.; Wickenden, Alan D.; Hermann, Michelle; Allison, Brett; Hawryluk, Natalie; Breitenbucher, J. Guy; Grice, Cheryl A.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5197 - 5201
反应条件
1: ammonium hydroxide / water / 20 - 25 °C 2: neat (no solvent) / 60 - 70 °C View Scheme
参考文献
Popov; Mokhov; Tankabekyan
Russian Journal of Organic Chemistry, 2014 , vol. 50, # 1 p. 21 - 24
Zh. Org. Khim., 2014 , vol. 50, # 1 p. 29 - 32,4
参考文献
Koetz; Merkel
Journal fuer Praktische Chemie (Leipzig), 1926 , vol. <2> 113, p. 74
反应条件
sodium hydrogensulfite
参考文献
Ahmadi; Kermani; Naderi; Hajikhani; Rezaee; Javadi; Niknafs
Current Medicinal Chemistry, 2012 , vol. 19, # 5 p. 763 - 769
反应条件
beim Behandeln des Hydrochlorids;
参考文献
Koetz; Merkel
Journal fuer Praktische Chemie (Leipzig), 1926 , vol. <2> 113, p. 74
