1-氟-4-苯基乙炔-苯合成路线 （共 39 条）
反应条件
triethylamine; palladium complex immobilised on silica gel in various solvent(s)
T=70°C; Sonogashira coupling; 12 h;
参考文献
Bandini, Marco; Luque, Rafael; Budarin, Vitaly; Macquarrie, Duncan J.
Tetrahedron, 2005 , vol. 61, # 41 p. 9860 - 9868
反应条件
palladium diacetate; triethylamine in N,N-dimethyl-formamide
T=100°C; Sonogashira coupling; 12 h;
参考文献
Hwang, Lee Kyoung; Na, Youngim; Lee, Junseong; Do, Youngkyu; Chang, Sukbok
Angewandte Chemie - International Edition, 2005 , vol. 44, # 38 p. 6166 - 6169
反应条件
copper(l) iodide; tetrabutylammomium bromide; potassium carbonate; triphenylphosphine; sodium iodide in water
T=120°C; 48 h; Inert atmosphere;
参考文献
Li, Tingyi; Sun, Peng; Yang, Hailong; Zhu, Yan; Yan, Hong; Lu, Linhua; Mao, Jincheng
Tetrahedron, 2012 , vol. 68, # 32 p. 6413 - 6419
反应条件
[bmim]PF6; triethylamine; Pd carbene
T=120°C; P=3800 Torr; 1 h;
参考文献
Rahman, Md. Taifur; Fukuyama, Takahide; Kamata, Naoya; Sato, Masaaki; Ryu, Ilhyong
Chemical Communications, 2006 , # 21 p. 2236 - 2238
反应条件
C32H28BrFeIN3Pd; potassium acetate; silver(l) oxide in 1,2-dichloro-ethane
T=80°C; 24 h;
参考文献
Li, Hong-Mei; Xu, Chen; Duan, Lu-Meng; Lou, Xin-Hua; Wang, Zhi-Qiang; Li, Zhen; Fan, Yao-Ting
Transition Metal Chemistry, 2013 , vol. 38, # 3 p. 313 - 318
反应条件
copper(l) iodide; cesium fluoride in toluene; acetonitrile
T=150°C; 0.5 h; Inert atmosphereMicrowave irradiation;
参考文献
Akubathini, Shashidhar Kumar; Biehl, Ed
Tetrahedron Letters, 2009 , vol. 50, # 16 p. 1809 - 1811
反应条件
2,6-dimethylpyridine; oxygen; copper(I) bromide in methanol
T=45°C; Sonogashira coupling; P=760.051 Torr; 16 h;
参考文献
Yasukawa, Tomohiro; Miyamura, Hiroyuki; Kobayashi, Sh
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 18 p. 6208 - 6210
反应条件
n-butyl-magnesium chloride; sodium methylate; sodium; Ca(OH)2 in tetrahydrofuran
T=0°C; 0.0916667 h; Inert atmosphereReflux;
参考文献
Jin, Guanyi; Zhang, Xuxue; Cao, Song
Organic Letters, 2013 , vol. 15, # 12 p. 3114 - 3117
反应条件
N-ethyl-N,N-diisopropylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in water; isopropyl alcohol
T=100°C; Suzuki coupling; 0.166667 h; microwave irradiation;
参考文献
Kabalka, George W.; Al-Masum, Mohammad; Mereddy, Arjun R.; Dadush, Eric
Tetrahedron Letters, 2006 , vol. 47, # 7 p. 1133 - 1136
反应条件
methanol; tri-tert-butyl phosphine; palladium diacetate; potassium carbonate in N,N-dimethyl acetamide
T=100°C; 2 h; Inert atmosphere; regioselective reaction;
参考文献
Sakai, Norio; Komatsu, Ryosuke; Uchida, Naoki; Ikeda, Reiko; Konakahara, Takeo
Organic Letters, 2010 , vol. 12, # 6 p. 1300 - 1303
