1-氯-4-(4-甲氧基苯氧基)苯合成路线 （共 20 条）
参考文献
Huang
Journal of the Chemical Society, 1954 , p. 3084,3087
反应条件
1: aq. HBr / acetic acid 2: (i) NaOEt, (ii) KOH, EtOH View Scheme
参考文献
Laboratoire L.Lafon.
Patent: FR2285861DE2543179 , 19761976 ;
Chem.Abstr., 1976 , vol. 85, # 20843
反应条件
1: With boron tribromide in dichloromethane T=-78 - 20°C; 2.08333 h; 2: With water in dichloromethane T=0°C; Product distribution / selectivity;
参考文献
DECODE CHEMISTRY, INC.
Patent: US2007/66820 A1, 2007 ;
Location in patent: Page/Page column 25; 27; 29 ;
US 20070066820 A1
反应条件
copper(l) iodide; iron (III) acetylacetonate; potassium carbonate in N,N-dimethyl-formamide
T=135°C; 12 h; Inert atmosphere;
参考文献
Liu, Xiaoyan; Zhang, Songlin
Synlett, 2011 , # 2 art. no. W15810ST, p. 268 - 272
反应条件
copper(l) iodide; glycine-N',N'-dimethylamide hydrochloride; caesium carbonate in 1,4-dioxane
T=90°C; Product distribution / selectivity;
参考文献
DECODE CHEMISTRY, INC.
Patent: US2007/66820 A1, 2007 ;
Location in patent: Page/Page column 27; 29 ;
US 20070066820 A1
反应条件
potassium phosphate; Cu(2,2'-bipyridyl)2BF4 in N,N-dimethyl-formamide
T=110°C; 48 h;
参考文献
Niu, Jiajia; Zhou, Hua; Li, Zhigang; Xu, Jingwei; Hu, Shaojing
Journal of Organic Chemistry, 2008 , vol. 73, # 19 p. 7814 - 7817
反应条件
copper(l) iodide; glycine-N',N'-dimethylamide hydrochloride; caesium carbonate in 1,4-dioxane
T=90°C; Ullmann coupling reaction; 24 h;
参考文献
Ma, Dawei; Cai, Qian
Organic Letters, 2003 , vol. 5, # 21 p. 3799 - 3802
反应条件
potassium hydroxide in diethyl ether
参考文献
Societe Anonyme dite: Laboratoire L. Lafon
Patent: US4156011 A1, 1979 ;
反应条件
potassium carbonate in acetonitrile
T=50°C; 30 h;
参考文献
Kakinuma, Yohji; Moriyama, Katsuhiko; Togo, Hideo
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-F0786-OP, p. 183 - 188
反应条件
potassium carbonate in acetonitrile
T=50°C; 24 h;
参考文献
Kakinuma, Yohji; Moriyama, Katsuhiko; Togo, Hideo
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-F0786-OP, p. 183 - 188
