1,2-环己二酮环乙缩醛合成路线 （共 23 条）
反应条件
1: 87 percent / LiAlH4 / tetrahydrofuran / 8 h / Heating
2: 90 percent / pyridine, chromium trioxide, celite / CH2Cl2 / 0.67 h / 20 - 25 °C
View Scheme
参考文献
Vankar, Yashwant D.; Reddy, M. Venkatram; Chaudhuri, Narayan C.
Tetrahedron, 1994 , vol. 50, # 37 p. 11057 - 11078
反应条件
1: 80 percent / CuCl2, CuO / acetone; H2O / 0.5 h / 35 °C
2: 53 percent / BF3*OEt2 / CH2Cl2 / 5 h / 20 °C
View Scheme
参考文献
Gregoire, Brigitte; Carre, Marie-Christiane; Caubere, Paul
Journal of Organic Chemistry, 1986 , vol. 51, # 9 p. 1419 - 1427
反应条件
1: 1.) NaNH2, Et(OCH2CH2)2OH / 1.) THF, 2 h, 2.) THF
2: 80 percent / CuCl2, CuO / acetone; H2O / 0.5 h / 35 °C
3: 53 percent / BF3*OEt2 / CH2Cl2 / 5 h / 20 °C
View Scheme
参考文献
Gregoire, Brigitte; Carre, Marie-Christiane; Caubere, Paul
Journal of Organic Chemistry, 1986 , vol. 51, # 9 p. 1419 - 1427
反应条件
toluene-4-sulfonic acid in toluene
8 h; Reflux;
参考文献
Elhawi, Hagit; Eini, Hadar; Douvdevani, Amos; Byk, Gerardo
Molecules, 2012 , vol. 17, # 6 p. 6784 - 6807
反应条件
toluene-4-sulfonic acid; ethylene glycol; benzene
参考文献
Jaeger; Smith
Journal of the Chemical Society, 1955 , p. 160,164
参考文献
Rosenmund; Kositzke
Chemische Berichte, 1959 , vol. 92, p. 486,490
反应条件
1: benzene; benzenesulfonic acid
2: ethanolic KOH-solution
View Scheme
参考文献
Rosenmund; Kositzke
Chemische Berichte, 1959 , vol. 92, p. 486,490
反应条件
2: benzene; benzenesulfonic acid
3: ethanolic KOH-solution
View Scheme
参考文献
Rosenmund; Kositzke
Chemische Berichte, 1959 , vol. 92, p. 486,490
反应条件
1: tetrahydrofuran; diethyl ether / 14 h / -78 - 20 °C / Inert atmosphere
2: trifluoroacetic acid / water / 3 h / 0 - 20 °C
3: 200 °C / Inert atmosphere
View Scheme
参考文献
Elhawi, Hagit; Eini, Hadar; Douvdevani, Amos; Byk, Gerardo
Molecules, 2012 , vol. 17, # 6 p. 6784 - 6807
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Jaeger; Smith
Journal of the Chemical Society, 1955 , p. 160,164
