3-溴-2-羟基-5-甲氧基苯甲醛合成路线 （共 6 条）
反应条件
bromine; sodium acetate in acetic acid T=20°C; 1 h;
参考文献
Evano, Gwilherm; Schaus, Jennifer V.; Panek, James S.
Organic Letters, 2004 , vol. 6, # 4 p. 525 - 528
反应条件
bromine in chloroform T=0 - 20°C; 5 h;
参考文献
Wyeth
Patent: US2006/4087 A1, 2006 ;
Location in patent: Page/Page column 15; 21 ;
US 20060004087 A1
反应条件
bromine in chloroform
参考文献
Wyeth
Patent: US2003/171428 A1, 2003 ;
反应条件
1.1: Mg(OMe)2 / methanol 1.2: methanol; toluene / 2 h / 80 °C 1.3: aq. H2SO4 / methanol; toluene / 2 h / 50 °C 2.1: 76 percent / glacial acetic acid; NaOAc; Br2 / 3 h / cooling View Scheme
参考文献
McGarrigle; Murphy; Gilheany
Tetrahedron Asymmetry, 2004 , vol. 15, # 8 p. 1343 - 1354
参考文献
Rubenstein
Journal of the Chemical Society, 1925 , vol. 127, p. 2003
反应条件
potassium carbonate in acetone
5 h; Heating;
参考文献
Ohishi, Yoshitaka; Doi, Yoshio; Nakanishi, Teruo
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 11 p. 4260 - 4270
