反应条件
1: 100 percent / KOH / methanol / Ambient temperature; overnight 2: 1M H2SO4 / H2O / 3 h / Heating 3: 1) ammonium carbonate, 2) KOH / 1) diethylene glycol, 120-130 deg C, 1h, 2) 195 deg C, 3h 4: 1a) BuLi / 1a) THF, hexane, -70 deg C, 1b) 0 deg C, 1h, 2) THF, -40 deg C 5: molsieves (3 Angstroem), DDQ / toluene / Heating; one night 6: 89 percent Chromat. / 3M NaOH / ethanol / 1) 0 deg C, 2) r.t., 3h 7: 90 percent / transformed Escherichia coli cells View Scheme
参考文献
Berg, E. M. M. van den; Jansen, F. J. H. M.; Goede, A. T. J. W. de; Baldew, A. U.; Lugtenburg, J.
Recueil des Travaux Chimiques des Pays-Bas, 1990 , vol. 109, # 4 p. 287 - 297
