十二氢-4H,8H,12H-4a,8a,12alpha-三氮杂苯并菲合成路线 （共 35 条）
反应条件
anschliessend Behandlung des Reaktionsprodukts mit HCN;
参考文献
Boehme et al.
Chemische Berichte, 1959 , vol. 92, p. 1608,1612
反应条件
1: 2) Nitrilotriethanol / 1) CH2Cl2, 7 d, RT, 2 d, reflux, 2) ether, 2 h, RT 2: 95 percent / H2 / 10percent Pd/C / methanol / standard pressure View Scheme
参考文献
Hoffmann, Reinhard W.; Eichler, Guenter; Endesfelder, Andreas
Liebigs Annalen der Chemie, 1983 , # 11 p. 2000 - 2007
反应条件
triethylamine in acetonitrile T=30 - 35°C; 3 h;
参考文献
Fukawa, Hidemichi; Terao, Yoshiyasu; Achiwa, Kazuo; Sekiya, Minoru
Chemistry Letters, 1982 , p. 231 - 232
Title/Abstract Full Text Show Details
Fukawa, Hidemichi; Terao, Yoshiyasu; Achiwa, Kazuo; Sehiya, Minoru
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 1 p. 94 - 99
反应条件
triethylamine in acetonitrile T=55 - 60°C; 2.5 h;
参考文献
Fukawa, Hidemichi; Terao, Yoshiyasu; Achiwa, Kazuo; Sehiya, Minoru
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 1 p. 94 - 99
反应条件
hydrogen; platinum(IV) oxide in acetic acid heat of hydrogenation; Thermodynamic data;
参考文献
Wiberg, Kenneth B.; Nakaji, David Y.; Morgan, Kathleen M.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3527 - 3532
反应条件
T=50°C; 16 h; Inert atmosphere;
参考文献
Barker, Graeme; McGrath, Julia L.; Klapars, Artis; Stead, Darren; Zhou, George; Campos, Kevin R.; O'Brien, Peter
Journal of Organic Chemistry, 2011 , vol. 76, # 15 p. 5936 - 5953
参考文献
Schoepf et al.
Justus Liebigs Annalen der Chemie, 1948 , vol. 559, p. 1,22, 23
Chemische Berichte, 1951 , vol. 84, p. 690,698
参考文献
Schoepf et al.
Justus Liebigs Annalen der Chemie, 1948 , vol. 559, p. 1,22, 23
Chemische Berichte, 1951 , vol. 84, p. 690,698
反应条件
1: 70 percent / 1.25 h / 100 °C
2: 67 percent / conc. HCl / 8 h / Heating
View Scheme
参考文献
Solodenko, V. A.; Kukhar', V. P.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 12.1 p. 2399 - 2403
→
25343-57-12-乙酰基-1,4,5,6-四氢吡啶,2-乙酰基-1,4,5,6-四氢吡啶,1-(1,4,5,6-四氢-2-吡啶)-乙酮
反应条件
1: H2O / 1 h / Ambient temperature
2: 1) t-BuOCl, 2) Et3N / 1) Et2O, 1 h, r.t., 2) overnight
View Scheme
参考文献
Kimpe, Norbert De; Stevens, Christian
Journal of Organic Chemistry, 1993 , vol. 58, # 10 p. 2904 - 2906
