1: 3-iodo-pyridine With diisobutylaluminium hydride; magnesium; lithium chloride in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: 1-iodo-n-octane With N,N,N',N,-tetramethylethylenediamine; ((Me)N2N)Ni-Cl in tetrahydrofuran Kumada-Corriu-Tamao coupling reaction; 2 h; Inert atmosphere;

potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp in xylene T=130°C; Suzuki cross-coupling; 20 h;

1: 1-bromo-octane With magnesium in diethyl ether Heating; 2: 3-bromo-pyridine With Cl2Ni(1,2-bis(diphenylphosphino)ethane) in diethyl ether Heating; Further stages.;

Ni-Cu-Cr-Na2SO4 on silica gel T=380 - 400°C; P=760 Torr;

chromium; silica gel; nickel; copper; sodium sulfate T=380 - 400°C;