反应条件
1: 1) Et3N, ethyl chloroformate 2) Et3N / 1) DMF, CHCl3, -5 to 0 deg C 2) DMF, CHCl3, 0 to 5 deg C, 1 h then RT, overnight
2: NH2OH*HCl, KOH / methanol / Ambient temperature
View Scheme
参考文献
Munakata; Tanaka; Toyoshima
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051