(R)-(-)-2-辛醇合成路线 (共 140 条)
反应条件
Rhodopirellula baltica DSM 10527; Tris buffer in water T=20°C; pH=7.5;
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 39 p. 6381 - 6384
反应条件
(1S,2R)-(-)-2-(N,N-di-n-butylamino)-1-phenylpropan-1-ol 1.) hexane, rt, 20 min 2.) hexane, 0 deg C, 16 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4264 - 4268
反应条件
polyoxyethylene (10) cetyl ether; n-octyl beta-D-glucopyranoside; subtilisin Carlsberg; sodium carbonate in tetrahydrofuran T=20°C; 15 h; Title compound not separated from byproducts;
参考文献
Chemistry - A European Journal, , vol. 12, # 1 p. 225 - 232
反应条件
water; sodium hydrogencarbonate T=37°C; pH=8 - 8.5; Green chemistryEnzymatic reaction; Reagent/catalystTime;
参考文献
Tetrahedron Asymmetry, , vol. 24, # 5-6 p. 249 - 253
反应条件
hydrogen; lipase B from Candida antarctica in toluene T=70°C; P=750.075 Torr; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
Xia, Bo; Cheng, Guilin; Lin, Xianfu; Wu, Qi
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2917 - 2923
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Iriye, Ryozo; Takai, Katsuki; Noguchi, Masakazu
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 2 p. 199 - 202
反应条件
alkylsulfatase from Rhodococcus ruber DSM 44541; tri-(hydroxymethyl)-methylamine in water T=20°C; pH=7.5; 120 h; Title compound not separated from byproducts;
参考文献
Angewandte Chemie - International Edition, , vol. 41, # 21 p. 4052 - 4054
反应条件
tri-n-butyl-tin hydride in dichloromethane T=18°C; 0.416667 h; Inert atmospherePhotolysis; enantioselective reaction;
参考文献
Hartung, Jens; Kempter, Irina; Gottwald, Thomas; Schwarz, Michaela; Kneuer, Rainer
Tetrahedron Asymmetry, 2009 , vol. 20, # 18 p. 2097 - 2104
反应条件
KNO2 in dimethyl sulfoxide T=65°C; 3.5 h;
参考文献
Synthesis, , vol. NO.4, p. 292 - 295
参考文献
Goergens, Ulrich; Schneider, Manfred P.
Tetrahedron: Asymmetry, 1992 , vol. 3, # 9 p. 1149 - 1152