2,2-二乙氧基乙酸乙酯合成路线 （共 88 条）
反应条件
in diethyl ether T=-78°C;
参考文献
Haegele, Gerhard; Haas, Andreas
Journal of Fluorine Chemistry, 1996 , vol. 76, # 1 p. 15 - 19
反应条件
1: 82 percent / acetyl chloride / iodine / 1 h / 50 °C 2: 84 percent / CHCl3 / 25 h / 25 °C View Scheme
参考文献
Bach, Karen K.; El-Seedi, Hesham R.; Jensen, Henrik M.; Nielsen, Helene B.; Thomsen, Ib; Torssell, B. G.
Tetrahedron, 1994 , vol. 50, # 25 p. 7543 - 7556
反应条件
1: acetyl chloride; iodine 2: 150 °C View Scheme
参考文献
Deussen, Heinz-Josef; Zundel, Magali; Valdois, Marine; Lehmann, Soren Vig; Weil, Volker; Mailand Hjort, Carsten; stergaard, Peter Rahbek; Marcussen, Erik; Ebdrup, Soren
Organic Process Research and Development, 2003 , vol. 7, # 1 p. 82 - 88
反应条件
(i) PCl5, (ii) /BRN= 956578/; Multistep reaction;
参考文献
Grell,W.; Machleidt,H.
Justus Liebigs Annalen der Chemie, 1966 , vol. 699, p. 53 - 67
反应条件
1: acetyl chloride; iodine 2: 150 °C 3: potassium tert-butylate / toluene 4: hydrogen; acetic acid / ethanol / 1500.15 - 4500.45 Torr View Scheme
参考文献
Organic Process Research and Development, , vol. 7, # 1 p. 82 - 88
反应条件
sodium hydride in methanol; toluene T=-10 - -8°C; 3 h;
参考文献
Werner, Andreas; Sanchez-Migallon, Ana; Fruchier, Alain; Elguero, Jose; Fernandez-Castano, Cristina; Foces-Foces, Concepcion
Tetrahedron, 1995 , vol. 51, # 16 p. 4779 - 4800
反应条件
boron trifluoride diethyl etherate in dichloromethane
6 h; Ambient temperature;
参考文献
Amat, Mercedes; Linares, Ana; Bosch, Joan
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6299 - 6312
参考文献
Wohl; Lange
Chemische Berichte, 1908 , vol. 41, p. 3615
反应条件
1: concentrated NH3
2: P2O5; quinoline
3: alcoholic HCl / 0 °C / Zerlegung des entstandenen Hydrochlorids mit K2CO3-Loesung bei -5grad
View Scheme
参考文献
McElvain; Clarke
Journal of the American Chemical Society, 1947 , vol. 69, p. 2660
反应条件
1: 55 percent / NH4OH, NH4Cl / H2O
2: 64 percent / P2S5 / benzene / Ambient temperature
3: 89 percent / 4 Angstroems molecular sieves / ethanol
View Scheme
参考文献
Inami; Shiba
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 1 p. 352 - 360
