1-氯-1-乙炔基-环己烷合成路线 （共 11 条）
反应条件
1: 1-bromo-2,3,4,5,6-pentafluorobenzene With cadmium in N,N-dimethyl-formamide T=20°C; 5 h; Inert atmosphere; 2: 1-ethynyl-1-chlorocyclohexane With copper(l) chloride in N,N-dimethyl-formamide
参考文献
Burton, Donald J.; Hartgraves, Greg A.
Journal of Fluorine Chemistry, 2009 , vol. 130, # 2 p. 254 - 258
参考文献
Hennion; Teach
Journal of the American Chemical Society, 1953 , vol. 75, p. 1653
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triethylamine; bis[2-(diphenylphosphino)phenyl] ether in tetrahydrofuran T=68°C; 1.5 h; Inert atmosphere;
参考文献
Kalek, Marcin; Stawinski, Jacek
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 10 p. 1741 - 1755
反应条件
1: in tetrahydrofuran; hexane
T=-85°C; 0.25 h;
2: With chloro-trimethyl-silane; oxygen; zinc(II) chloride in tetrahydrofuran; hexane
T=-85 - -40°C;
参考文献
Harada, Toshiro; Kutsuwa, Emiko
Journal of Organic Chemistry, 2003 , vol. 68, # 17 p. 6716 - 6719
反应条件
N,N,N',N,-tetramethylethylenediamine
T=30°C; 24 h; Yield given. Yields of byproduct given;
参考文献
Bridges, Alexander J.
Tetrahedron Letters, 1980 , vol. 21, p. 4401 - 4404
反应条件
in N,N-dimethyl-formamide
T=20°C;
参考文献
Burton, Donald J.; Hartgraves, Greg A.
Journal of Fluorine Chemistry, 2007 , vol. 128, # 10 p. 1198 - 1215
参考文献
Larock, R. C.; Varaprath, S.; Lau, H. H.; Fellows, C. A.
Journal of the American Chemical Society, 1984 , vol. 106, # 18 p. 5274 - 5284
参考文献
Hennion; Nelson
Journal of the American Chemical Society, 1957 , vol. 79, p. 2142,2144
参考文献
Hennion,G.F.; Boisselle,A.P.
Journal of Organic Chemistry, 1961 , vol. 26, p. 2677 - 2681
参考文献
Larock, R. C.; Varaprath, S.; Lau, H. H.; Fellows, C. A.
Journal of the American Chemical Society, 1984 , vol. 106, # 18 p. 5274 - 5284
