反应条件
1: caesium carbonate / hydroxybenzaldoxime; copper(II) oxide / acetonitrile / 24 h / 80 °C / Inert atmosphere 2: nitric acid; sulfuric acid / -5 - 20 °C / Cooling with ice 3: hydrogen / 5 palladium on charcoal / tetrahydrofuran / Inert atmosphere 4: trifluoroacetic acid; sodium tris(acetoxy)borohydride / isopropanol acetate / 4.5 h / 20 °C / Inert atmosphere View Scheme
参考文献
DOW AGROSCIENCES LLC; Buysse, Ann M.; Niyaz, Noormohamed M.; Demeter, David A.; Zhang, Yu; Walsh, Martin J.; Kubota, Asako; Hunter, Ricky; Trullinger, Tony K.; Lowe, Christian T.; Knueppel, Daniel; Patny, Akshay; Garizi, Negar; LePlae, JR., Paul Renee; Wessels, Frank; Ross, JR., Ronald; DeAmicis, Carl; Borromeo, Peter
Patent: US2013/288893 A1, 2013 ;