2,3-二溴-3-苯基丙酸合成路线 （共 90 条）
反应条件
1: copper(l) iodide; sodium azide; caesium carbonate; sodium L-ascorbate / dimethyl sulfoxide / 4 h / 110 °C / Inert atmosphere 2: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C View Scheme
参考文献
Huang, Qiang; Zheng, Maofa; Yang, Shuangshuang; Kuang, Chunxiang; Yu, Cunjing; Yang, Qing
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 11 p. 5680 - 5687
反应条件
1: natrium carbonate 2: diethyl ether; sodium 3: absolute diethyl ether View Scheme
参考文献
Nef
Justus Liebigs Annalen der Chemie, 1899 , vol. 308, p. 325
反应条件
sodium tetrahydroborate; nickel dichloride in methanol T=20°C; 0.25 h;
参考文献
Khurana, Jitender M.; Kandpal, Bhaskar M.; Kukreja, Gagan; Sharma, Purnima
Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1019 - 1023
反应条件
aluminium; nickel dichloride in tetrahydrofuran Dehalogenation;
参考文献
Sarmah, Parijat; Sarma, Bhabani K.; Barua, Nabin C.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997 , vol. 36, # 6 p. 528 - 529
参考文献
Paulson; MacGregor
Journal of the American Chemical Society, 1951 , vol. 73, p. 679
反应条件
sodium hydride in dimethyl sulfoxide T=20°C; 12 h; Sealed tube;
参考文献
Cheng, Xue-Zhi; Liu, Wei; Huang, Zhen-Dong; Kuang, Chun-Xiang
Chinese Chemical Letters, 2013 , vol. 24, # 8 p. 764 - 766
反应条件
1: natrium carbonate 2: diethyl ether; sodium 3: absolute diethyl ether 4: concentrated sulfuric acid View Scheme
参考文献
Nef
Justus Liebigs Annalen der Chemie, 1899 , vol. 308, p. 325
反应条件
1: natrium carbonate 2: diethyl ether; sodium 3: diethyl ether View Scheme
参考文献
Gitsels; Wibaut
Recueil des Travaux Chimiques des Pays-Bas, 1940 , vol. 59, p. 1093,1100
反应条件
silver(l) oxide ethyl ester of inactive cinnamic acid dibromide;
参考文献
Sudborough; Thompson
Journal of the Chemical Society, 1903 , vol. 83, p. 673
反应条件
potassium hydroxide in methanol Heating;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 37, # 3 p. 288 - 293
