反应条件
1: 86 percent / 47percent HBr / heptane / Heating
2: 84 percent / H+ / diethyl ether
3: 1.) Mg / 1.) THF, 4 h, reflux, 2.) THF, -5 deg C, 16 h
4: 90 percent / PCC / CH2Cl2 / 24 h / Ambient temperature
5: 1.) HCl / 1.) CH3OH, 2.) pyridine, room temperature, 3 h
6: 90 percent / NaBr / dimethylformamide / 40 h / 45 °C
View Scheme
参考文献
Braconnier, M.F.; Braekman, J.C.; Daloze, D.
Bulletin des Societes Chimiques Belges, 1985 , vol. 94, # 8 p. 605 - 614
