2,4-二羟基-5-氯苯甲酸合成路线 （共 14 条）
反应条件
1: With AlCl3, aluminium chloride; lauryl mercaptan T=40°C; 1.08333 h; 2: With water in ethyl acetate; lauryl mercaptan T=0 - 20°C;
参考文献
ASTRAZENECA AB
Patent: WO2008/10765 A1, 2008 ;
Location in patent: Page/Page column 61 ;
WO 2008/010765 A1
反应条件
sodium hydroxide in methanol 4 h; Heating;
参考文献
Blagg, Brian; Shen, Gang; Clevenger, Randell C.
Patent: US2006/89495 A1, 2006 ;
Location in patent: Page/Page column 22 ;
反应条件
1: 62 percent / sulfuryl chloride / CH2Cl2 / 19 h / 0 - 25 °C 2: 96 percent / NaOH / methanol / 4 h / Heating View Scheme
参考文献
Organic Letters, , vol. 7, # 11 p. 2157 - 2160
反应条件
1: SO2Cl2 / CHCl3 / Heating 2: (i) Py*HCl, (ii) aq. NaOH View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 878 - 882
反应条件
chlorine; acetic acid
参考文献
Monatshefte fuer Chemie, , vol. 46, p. 155
反应条件
1: sodium methylate / 100 °C / 4560 Torr 2: diethyl ether; sulfuryl chloride View Scheme
参考文献
Annales de Chimie (Cachan, France), , vol. <9> 18, p. 81
反应条件
(i) Py*HCl, (ii) aq. NaOH; Multistep reaction;
参考文献
Bulletin de la Societe Chimique de France, , p. 878 - 882
参考文献
Annales de Chimie (Cachan, France), , vol. <9> 18, p. 81
Journal of the American Chemical Society, , vol. 57, p. 1077
参考文献
Annales de Chimie (Cachan, France), , vol. <9> 18, p. 81
参考文献
Annales de Chimie (Cachan, France), , vol. <9> 18, p. 81
Journal of the American Chemical Society, , vol. 57, p. 1077
