N-甲氧基-N-甲基苯甲酰胺合成路线 （共 140 条）
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-phenyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: cyclohexanone in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 3: 2,2,2-Trifluoro-1-phenyl-ethanone in tetrahydrofuran; diethyl ether T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-phenyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: butyraldehyde in tetrahydrofuran; diethyl ether T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-phenyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: cyclohexanecarbaldehyde in tetrahydrofuran; diethyl ether T=20°C; 2 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
in tetrahydrofuran T=22°C;
参考文献
Whipple, Wesley L.; Reich, Hans J.
Journal of Organic Chemistry, 1991 , vol. 56, # 8 p. 2911 - 2912
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-phenyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: butyraldehyde in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 3: 2,2,2-Trifluoro-1-phenyl-ethanone in tetrahydrofuran; diethyl ether T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
4-(N,N-dimethlyamino)pyridine; potassium phosphate; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=110°C; Heck reaction; 0.166667 h; Microwave irradiation;
参考文献
Wieckowska, Anna; Fransson, Rebecca; Odell, Luke R.; Larhed, Mats
Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 978 - 981
反应条件
in tetrahydrofuran; diethyl ether; cyclohexane T=-78°C; 1 h;
参考文献
Hlasta, Dennis J.; Court, John J.
Tetrahedron Letters, 1989 , vol. 30, # 14 p. 1773 - 1776
反应条件
ozone in dichloromethane T=-78°C;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 53, # 8 p. 2407 - 2408
反应条件
1: 97 percent / 5 Angstroem molecular sieves / CH2Cl2 / 3 h / 23 °C 2: 47.4 mg / ZrCl4 / acetonitrile; CH2Cl2 / 1 h / 23 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 50 p. 16406 - 16409
反应条件
4-(N,N-dimethlyamino)pyridine; potassium phosphate; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=120°C; Heck reaction; 0.333333 h; Microwave irradiation;
参考文献
Wieckowska, Anna; Fransson, Rebecca; Odell, Luke R.; Larhed, Mats
Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 978 - 981
