1: n-butyl-magnesium bromide; Bromure de phenyl magnesium With manganese (II) chloride in tetrahydrofuran
T=0°C; transmetalation; 0.333333 h;
2: cyclohexanecarbaldehyde in tetrahydrofuran
T=-78°C; Addition; 0.333333 h;
参考文献
Yorimitsu, Hideki; Hayashi, Yasuhiro; Tang, Jun; Shinokubo, Hiroshi; Oshima, Koichiro
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 9 p. 2297 - 2300
1: n-butyl-magnesium bromide; methylmagnesium bromide With manganese (II) chloride in tetrahydrofuran
T=0°C; transmetalation; 0.333333 h;
2: cyclohexanecarbaldehyde in tetrahydrofuran
T=-78°C; Addition; 0.333333 h;
参考文献
Yorimitsu, Hideki; Hayashi, Yasuhiro; Tang, Jun; Shinokubo, Hiroshi; Oshima, Koichiro
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 9 p. 2297 - 2300
1: n-butyl-magnesium bromide; n-C6H13CCMgX With manganese (II) chloride in tetrahydrofuran
T=0°C; transmetalation; 0.333333 h;
2: cyclohexanecarbaldehyde in tetrahydrofuran
T=-78°C; Addition; 0.333333 h;
参考文献
Yorimitsu, Hideki; Hayashi, Yasuhiro; Tang, Jun; Shinokubo, Hiroshi; Oshima, Koichiro
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 9 p. 2297 - 2300
sulfuric acid; benzene in diethyl ether
byproducts: H2O; addn. of 1.66mol RMgBr in ether to 0.53mol B(OCH3)3 in ether at -75°C, stiiring at -70°C (4h), warming slowly to -10°C, hydrolysis with 10percent H2SO4, separation of organic phase, removal of solvent, boiling of residue with C6H6;;
参考文献
McCusker et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5179
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Gmelin Handbook: B: B-Verb.13, 4.7.2.2, page 189 - 196
