2-氨基-5-氯二苯甲酮合成路线 （共 174 条）
反应条件
camphor-10-sulfonic acid in ethanol 2.3 h; Reflux;
参考文献
Paul, Nidhin; Muthusubramanian, Shanmugam
Synthetic Communications, 2013 , vol. 43, # 8 p. 1200 - 1209
参考文献
Bahr; Dietz
Pharmazie, 1980 , vol. 35, # 5-6 p. 256 - 263
反应条件
[HBIM](1+)*BF4(1-)
T=100°C; Friedlaender reaction; 6 h;
参考文献
Palimkar, Sanjay S.; Siddiqui, Shapi A.; Daniel, Thomas; Lahoti, Rajgopal J.; Srinivasan, Kumar V.
Journal of Organic Chemistry, 2003 , vol. 68, # 24 p. 9371 - 9378
反应条件
zinc trifluoromethanesulfonate; [C6mim][PF6]
T=80 - 90°C; Meyer-Schuster rearrangement; 2.5 h; Heating;
参考文献
Mohammadpoor-Baltork, Iraj; Tangestaninejad, Shahram; Moghadam, Majid; Mirkhani, Valiollah; Anvar, Salma; Mirjafari, Arsalan
Synlett, 2010 , # 20 art. no. D19310ST, p. 3104 - 3112
反应条件
copper(II) bis(trifluoromethanesulfonate) in neat (no solvent)
T=110°C;
参考文献
Bagdi, Avik Kumar; Santra, Sougata; Rahman, Matiur; Majee, Adinath; Hajra, Alakananda
RSC Advances, 2013 , vol. 3, # 46 p. 24034 - 24037
反应条件
benzophenone; cis-[RuCl2(dimethylsulfoxide-S)3(dimethylsulfoxide-O)]; potassium tert-butylate
T=100°C; indirect Friedlaender annulation; 48 h;
参考文献
Martinez, Ricardo; Ramon, Diego J.; Yus, Miguel
European Journal of Organic Chemistry, 2007 , # 10 p. 1599 - 1605
反应条件
pyridine in chloroform
1 h; Ambient temperature;
参考文献
Richter; Kasbohm; Besch; Hagen
Pharmazie, 1992 , vol. 47, # 10 p. 758 - 764
反应条件
aluminium trichloride
1.) 25 deg C, 1 h, 2.) ether, room temp., 3 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Acharya, Baman Prasad; Rao, Y. Ramachandra
Journal of Chemical Research, Miniprint, 1987 , # 4 p. 1001 - 1035
反应条件
potassium iodide; sulfuric acid; sodium nitrite in water; Petroleum ether
参考文献
Hoffmann-La Roche Inc.
Patent: US4469633 A1, 1984 ;
Title/Abstract Full Text Show Details
Hoffmann-La Roche Inc.
Patent: US4318854 A1, 1982 ;
反应条件
sulfuric acid; potassium iodide; sodium nitrite
1.) 1 h, 2.) room temp., overnight; Yield given. Multistep reaction;
参考文献
Trybulski, Eugene J.; Reeder, Earl; Blount, John F.; Walser, Armin; Fryer, R. Ian
Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2441 - 2447
