3-(1-哌啶基)苯丙酮盐酸盐合成路线 (共 25 条)
反应条件
potassium fluoride in dichloromethane 16 h; Heating; Yield given;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 61, # 3 p. 735 - 740
反应条件
1: NaI / acetone 2: acetonitrile / 25 °C View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 10 p. 1918 - 1921
Zhurnal Organicheskoi Khimii, , vol. 22, # 10 p. 2138 - 2142
参考文献
Journal of the American Chemical Society, , vol. 52, p. 235,239
反应条件
in ethanol; benzene 10 h; Heating;
参考文献
European Journal of Medicinal Chemistry, , vol. 31, # 4 p. 281 - 290
参考文献
Chemische Berichte, , vol. 55, p. 3518
DE379950 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1247
反应条件
water in tetrahydrofuran T=20°C; Substitution; Michael reaction; Product distribution;
参考文献
Organic Letters, , vol. 2, # 1 p. 11 - 13
参考文献
Archiv der Pharmazie (Weinheim, Germany), , p. 746
反应条件
in acetonitrile T=25°C;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 10 p. 1918 - 1921
Zhurnal Organicheskoi Khimii, , vol. 22, # 10 p. 2138 - 2142
反应条件
in acetonitrile T=25°C; Rate constantMechanism;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 7 p. 1299 - 1302
Zhurnal Organicheskoi Khimii, , vol. 22, # 7 p. 1442 - 1446
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=20°C; 1 h; 2: 1-phenyl-3-(piperidin-1-yl)propan-1-one in tetrahydrofuran; hexane T=20°C; Wittig olefination; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 70, # 14 p. 5528 - 5535