(2,2-二溴乙烯基)苯合成路线 （共 99 条）
反应条件
1: BrCl / CH2Cl2
2: sodium methoxide / methanol / 30 °C
View Scheme
参考文献
Montani, Rosana S.; Garay, Raul O.; Cabaleiro, Mercedes C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 1125 - 1130
反应条件
1: ozone; 4-methylmorpholine N-oxide; oxygen / dichloromethane / 0.25 h / -78 °C / |Inert atmosphere
2: zinc; triphenylphosphine / dichloromethane / |Inert atmosphere
View Scheme
参考文献
Brown, Brenna Arlyce; Veinot, Jonathan G.C.
Tetrahedron Letters, 2013 , vol. 54, # 8 p. 792 - 795
反应条件
(i) Ph3P, KOtBu, heptane, (ii) /BRN= 471223/; Multistep reaction;
参考文献
Speziale,A.J.; Ratts,K.W.
Journal of the American Chemical Society, 1962 , vol. 84, p. 854 - 859
反应条件
bromine; sodium methylate
1.) dichloromethane, - 78 deg C, 30 min; 0 deg C, 30 min, 2.) methanol, 0 deg C, 30 min; 25 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Fisher, Richard P.; On, Harry P.; Snow, John T.; Zweifel, George
Synthesis, 1982 , # 2 p. 127 - 129
反应条件
in dichloromethane
0.5 h; Ambient temperature;
参考文献
Bestmann, Hans Juergen; Frey, Herbert
Liebigs Annalen der Chemie, 1980 , # 12 p. 2061 - 2071
反应条件
sodium methylate in methanol
T=30°C;
参考文献
Montani, Rosana S.; Garay, Raul O.; Cabaleiro, Mercedes C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 1125 - 1130
反应条件
sodium methylate in methanol
T=30°C;
参考文献
Montani, Rosana S.; Garay, Raul O.; Cabaleiro, Mercedes C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 1125 - 1130
反应条件
(i) nBuLi, LiBr, THF, Et2O, (ii) /BRN= 471223/, LDA; Multistep reaction;
参考文献
Savignac,P.; Coutrot,P.
Synthesis, 1976 , p. 197 - 199
反应条件
[2,2']bipyridinyl; potassium phosphate; nickel dichloride; zinc in N,N-dimethyl-formamide
T=80°C; 20 h; Schlenk technique; stereoselective reaction;
参考文献
Liu, Liu; Lv, Ye; Wu, Yile; Gao, Xiang; Zeng, Zhiping; Gao, Yuxing; Tang, Guo; Zhao, Yufen
RSC Advances, 2014 , vol. 4, # 5 p. 2322 - 2326
反应条件
potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine in toluene
T=120°C; Inert atmosphere; optical yield given as percent destereoselective reaction;
参考文献
Jouvin, Kevin; Coste, Alexis; Bayle, Alexandre; Legrand, Frederic; Karthikeyan, Ganesan; Tadiparthi, Krishnaji; Evano, Gwilherm
Organometallics, 2012 , vol. 31, # 22 p. 7933 - 7947
