环己基-(4-甲氧基-苯基)-甲酮合成路线 （共 19 条）
反应条件
indium in 1,4-dioxane
Friedel-Crafts acylation; 4 h; Heating;
参考文献
Jang, Doo Ok; Moon, Kyung Soo; Cho, Dae Hyan; Kim, Joong-Gon
Tetrahedron Letters, 2006 , vol. 47, # 34 p. 6063 - 6066
反应条件
methanesulfonic acid; carbon
T=80°C; Friedel-Crafts acylation; 0.0833333 h;
参考文献
Sarvari, Mona Hosseini; Sharghi, Hashem
Synthesis, 2004 , # 13 p. 2165 - 2168
反应条件
ytterbium(III) triflate in nitromethane; methoxybenzene
参考文献
Kirin Beer Kabushiki Kaisha
Patent: US6143764 A1, 2000 ;
反应条件
triethylamine; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane
T=80°C; 3 h;
参考文献
Rao, Maddali L.N.; Venkatesh, Varadhachari; Banerjee, Debasis
Tetrahedron, 2007 , vol. 63, # 52 p. 12917 - 12926
反应条件
2,9-dimethyl-1,10-phenanthroline; oxygen; sodium hydrogencarbonate; gold(I) chloride in water
T=100°C; P=38002.6 Torr; 24 h;
参考文献
Li, Huanrong; Guan, Bingtao; Wang, Wenjin; Xing, Dong; Fang, Zhao; Wan, Xiaobing; Yang, Liping; Shi, Zhangjie
Tetrahedron, 2007 , vol. 63, # 35 p. 8430 - 8434
反应条件
1: 70 percent / acetic acid
2: sodium tert-butoxide / Pd2(dba)3; bis(2-diphenylphosphinophenyl)ether / dioxane / 24 h / 80 °C
3: 86.3 mg / sulfuric acid / tetrahydrofuran; H2O / 24 h / 20 °C
View Scheme
参考文献
Takemiya, Akihiro; Hartwig, John F.
Journal of the American Chemical Society, 2006 , vol. 128, # 46 p. 14800 - 14801
反应条件
1: cyclohexanecarboxylic acid tert-butyl ester With indium tribromide; dimethylmono-chlorosilane in 1,2-dichloro-ethane
T=20°C; 2 h; Inert atmosphere;
2: methoxybenzene in 1,2-dichloro-ethane
T=90°C; Friedel Crafts acylation; 5 h; regioselective reaction;
参考文献
Nishimoto, Yoshihiro; Babu, Srinivasarao Arulananda; Yasuda, Makoto; Baba, Akio
Journal of Organic Chemistry, 2008 , vol. 73, # 23 p. 9465 - 9468
反应条件
3,3-dimethyl-butan-2-one; [Ru(CO)3Cl2]2; K3PO4*3H2O; [(t-Bu)3PH]BF4 in water; toluene
T=100°C; 24 h; Inert atmosphere;
参考文献
Li, Hong; Xu, Yuan; Shi, Erbo; Wei, Wei; Suo, Xiangqiang; Wan, Xiaobing
Chemical Communications, 2011 , vol. 47, # 27 p. 7880 - 7882
反应条件
1: 1-bromo-4-methoxy-benzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: cyclohexanecarbaldehyde in tetrahydrofuran; hexane
T=-78°C; 2 h;
3: With iodine; potassium carbonate in tert-butyl alcohol
27 h; Reflux;
参考文献
Ushijima, Sousuke; Dohi, Souya; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2012 , vol. 68, # 5 p. 1436 - 1442
反应条件
titanium tetrachloride; zinc in ethylene glycol dimethyl ether
T=20°C; 24 h;
参考文献
Sakurai, Hidehiro; Imamoto, Yuka; Hirao, Toshikazu
Chemistry Letters, 2002 , # 1 p. 44 - 45
