4-甲基-1，3-戊二烯合成路线 （共 99 条）
反应条件
1: 71 percent / phosphoryl chloride, activated Zn / diethyl ether / 12 h / Ambient temperature
2: 90 percent / Zn, aq. acetic acid / 80 h / Ambient temperature
View Scheme
参考文献
Brady, William T.; Norton, Scott J.; Ko, Jinren
Synthesis, 1983 , # 12 p. 1002 - 1005
参考文献
Bachman; Hatton
Journal of the American Chemical Society, 1944 , vol. 66, p. 1513
参考文献
Lewina et al.
Sb. Statei Obshch. Khim., 1953 , p. 355,359
Chem.Abstr., 1955 , p. 829
反应条件
(i) K, Et3N, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Yasuda,H. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 2036 - 2045
反应条件
hydrogen bromide in acetic acid
参考文献
Firmenich SA
Patent: US3931326 A1, 1976 ;
反应条件
1: 2-methyl-2,4-pentadiene With isopropylmagnesium chloride; [NiCl2Py4] in tetrahydrofuran
T=20°C; Addition; Hydromagnesation; 40 h;
2: carbon dioxide in tetrahydrofuran
Carboxylation;
参考文献
Viktorov; Zubritskii
Russian Journal of Organic Chemistry, 1999 , vol. 35, # 12 p. 1755 - 1765
反应条件
1: tBuOK / -10 °C
2: 100 percent Chromat. / 1.6 M MeLi / diethyl ether / 1 h / -78 °C
View Scheme
参考文献
Holm, Kjetil H.; Skatteboel, Lars
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1984 , vol. 38, # 9 p. 783 - 794
参考文献
Kohn; Morgenstern
Monatshefte fuer Chemie, 1907 , vol. 28, p. 490
参考文献
Slobodin
Zhurnal Obshchei Khimii, 1938 , vol. 8, p. 245,250
Chem. Zentralbl., 1939 , vol. 110, # II p. 66
