苯并[b]呋喃-7-甲醛合成路线 （共 14 条）
反应条件
1: 7-Bromobenzo[b]furan With magnesium; iodine in tetrahydrofuran T=85°C; 1.5 h; Heating / reflux; 2: N,N-dimethyl-formamide in tetrahydrofuran T=0 - 20°C; 0.5 h;
参考文献
Ajinomoto Co., Inc.
Patent: EP1878734 A1, 2008 ;
Location in patent: Page/Page column 13 ;
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloro difluoro methane T=-78°C; 0.5 h; 2: With triethylamine in dichloromethane T=-78 - 20°C;
参考文献
Bristol-Myers Squibb Company
Patent: EP1027043 B1, 2004 ;
Location in patent: Page/Page column 19 ;
反应条件
sodium hydroxide in 1,4-dioxane; ethyl acetate; Petroleum ether
参考文献
Synthelabo
Patent: US6063810 A1, 2000 ;
反应条件
Grubb's 2nd generation catalyst in toluene T=90°C; 3 h;
参考文献
Van Otterlo, Willem A.L.; Morgans, Garreth L.; Madeley, Lee G.; Kuzvidza, Samuel; Moleele, Simon S.; Thornton, Natalie; De Koning, Charles B.
Tetrahedron, 2005 , vol. 61, # 32 p. 7746 - 7755
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane 1.) CHCl3, reflux, 4 h; 2.) H2O, AcOH, reflux, 3 h;
参考文献
Benassi, Rois; Folli, Ugo; Iarossi, Dario; Schenetti, Luisa; Taddei, Ferdinando
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 9 p. 1479 - 1486
反应条件
1: microwave irradiation 2: 77 percent / K2CO3 / acetone / 2 h / 60 °C 3: 57 percent / [RuClH(CO)(PPh3)3] / CH2Cl2 / 14 h / 65 °C 4: 70 percent / ((Mes)2C3H5N2)Cl2Ru=CHPh / toluene / 3 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 61, # 32 p. 7746 - 7755
反应条件
1: K2CO3 / acetone 2: microwave irradiation 3: 77 percent / K2CO3 / acetone / 2 h / 60 °C 4: 57 percent / [RuClH(CO)(PPh3)3] / CH2Cl2 / 14 h / 65 °C 5: 70 percent / ((Mes)2C3H5N2)Cl2Ru=CHPh / toluene / 3 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 61, # 32 p. 7746 - 7755
反应条件
1: 77 percent / K2CO3 / acetone / 2 h / 60 °C 2: 57 percent / [RuClH(CO)(PPh3)3] / CH2Cl2 / 14 h / 65 °C 3: 70 percent / ((Mes)2C3H5N2)Cl2Ru=CHPh / toluene / 3 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 61, # 32 p. 7746 - 7755
反应条件
1: 57 percent / [RuClH(CO)(PPh3)3] / CH2Cl2 / 14 h / 65 °C 2: 70 percent / ((Mes)2C3H5N2)Cl2Ru=CHPh / toluene / 3 h / 90 °C View Scheme
参考文献
Tetrahedron, , vol. 61, # 32 p. 7746 - 7755
反应条件
1: 48 percent / benzoyl peroxide, N-bromosuccinimide / CCl4 / 8 h / Heating; Irradiation 2: 70 percent / 1.) hexamethylenetetramine / 1.) CHCl3, reflux, 4 h; 2.) H2O, AcOH, reflux, 3 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 9 p. 1479 - 1486
