(1S,2s)-反式-1,2-环己二醇合成路线 （共 85 条）
反应条件
(5aS,10bR)-5a,10b-dihydro-2-(pentafluorophenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium tetrafluoroborate; 3-benzylriboflavin tetraacetate; triethylamine in chloroform T=20°C; 3 h; Resolution of racemateAirMolecular sieve; optical yield given as percent eeenantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 17, # 29 p. 8009 - 8013
反应条件
1: trans-1,2-cyclohexanediol With (5aS,10bR)-9-nitro-2-phenyl-4,5a,6,10b-tetrahydroindeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-2-ium tetrafluoroborate; 4-(N,N-dimethylamino)benzoic acid; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in chloroform T=20°C; 0.166667 h; 2: 2-bromo-3-phenylpropanal in chloroform T=0°C; 17 h;
参考文献
Kuwano, Satoru; Harada, Shingo; Kang, Bubwoong; Oriez, Raphael; Yamaoka, Yousuke; Takasu, Kiyosei; Yamada, Ken-Ichi
Journal of the American Chemical Society, 2013 , vol. 135, # 31 p. 11485 - 11488
反应条件
hydrogen; CD; Pt/Al2O3 in toluene T=15°C; P=22501.8 Torr; Kinetics;
参考文献
Journal of Catalysis, , vol. 215, # 1 p. 116 - 121
反应条件
sodium tetrahydroborate
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 9 p. 1112 - 1115
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide in toluene T=0°C; Steglich esterification; 7 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2689 - 2690
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine in toluene T=0°C; Steglich esterification; 14 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2689 - 2690
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide in toluene T=0°C; Steglich esterification; 48 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2689 - 2690
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide in toluene T=0°C; Steglich esterification; 48 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2689 - 2690
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide in toluene T=0°C; Steglich esterification; 48 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2689 - 2690
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide in toluene T=0°C; Steglich esterification; 48 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2689 - 2690
