2-氨基-5-氯二苯甲酮合成路线 （共 174 条）
反应条件
sodium acetate 70 h; Heatingother aryl- and alkylketones, and anilines under various conditions; Product distributionMechanism;
参考文献
Peet, Norton P.; Sunder, Shyam; Barbuch, Robert J.; Whalon, Michael R.; Huber, Edward W.; Huffman, John C.
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1611 - 1618
参考文献
Hino; Furukawa; Nagai; Uno
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 9 p. 2618 - 2622
反应条件
1: 1) sodium hydride / 1) DMF, ice cooling, 2) 16 h, room temperature 2: 1) aqu. sodium nitrite, 2) sodium azide / 1) 1N aqueous hydrochloric acid, ice cooling, 2) pH 5, 30 min 3: 31 percent / dimethylsulfoxide / 2 h / 140 °C View Scheme
参考文献
Garanti, Luisa; Zecchi, Gaetano
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4767 - 4769
反应条件
1: With dirhodium tetraacetate in toluene T=80°C; 2: With 1,8-diazabicyclo[5.4.0]undec-7-ene in toluene T=20°C; Further stages.;
参考文献
Nakamura, Yoshinori; Ukita, Tatsuzo
Organic Letters, 2002 , vol. 4, # 14 p. 2317 - 2320
反应条件
copper(II) bis(trifluoromethanesulfonate) in neat (no solvent) T=110°C; 3 h; Reagent/catalystSolventTime;
参考文献
Bagdi, Avik Kumar; Santra, Sougata; Rahman, Matiur; Majee, Adinath; Hajra, Alakananda
RSC Advances, 2013 , vol. 3, # 46 p. 24034 - 24037
反应条件
citric acid T=100°C; Friedlaender synthesis; 5 h; neat (no solvent);
参考文献
Enugala, Ramu; Nuvvula, Sreelatha; Kotra, Vijay; Varala, Ravi; Adapa, Srinivas R.
Heterocycles, 2008 , vol. 75, # 10 p. 2523 - 2533
反应条件
tin(ll) chloride T=20°C; 0.75 h;
参考文献
Arumugam, Pandurangan; Karthikeyan, Ganesan; Atchudan, Raji; Muralidharan; Perumal, Paramasivan T.
Chemistry Letters, 2005 , vol. 34, # 3 p. 314 - 315
反应条件
Yield given. Multistep reaction;
参考文献
Mack, H. Michael; Davis, Everette A.; Kadkhodayan, Babak; Taylor, Richard A.; Duncan, Dean C.; Beam, Charles F.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1733 - 1740
反应条件
camphor-10-sulfonic acid in ethanol 2 h; Reflux;
参考文献
Paul, Nidhin; Muthusubramanian, Shanmugam
Synthetic Communications, 2013 , vol. 43, # 8 p. 1200 - 1209
反应条件
camphor-10-sulfonic acid in ethanol 2.5 h; Reflux;
参考文献
Paul, Nidhin; Muthusubramanian, Shanmugam
Synthetic Communications, 2013 , vol. 43, # 8 p. 1200 - 1209
